Researchers have developed scooby, a computational model that predicts genomic activity at unprecedented single-cell resolution directly from DNA sequence. The technology demonstrates significant improvements in capturing cell-type-specific regulation and transcription factor activities, according to findings published in Nature Methods.
Breakthrough in Single-Cell Genomics Prediction
Researchers have developed a new computational model called scooby that can predict genomic profiles at single-cell resolution directly from DNA sequence, according to a recent report in Nature Methods. The technology represents a significant advancement in understanding how individual cells interpret genetic information, with potential applications in developmental biology, cancer research, and personalized medicine.